I had the opportunity to finally test Windows 7 (RC) 64-bit with software 6.5R2 using JSAM.
I didn't have any issues with JSAM launching properly so I suspect the problem in 6.5R1 has been addressed in 6.5R2. I still need to test Network Connect and WSAM for compatibility with the security solutions that had major issues in the latest release, Norton 360, Symantec AntiVirus, ESET NOD32 and Zone Alarm.
Cheers!